“Under laboratory conditions, open mouth technique (holding MDI 2 inches away from open mouth) enhances delivery to the lung. This technique, however, has not been shown to enhance clinical benefit consistently compared to closed-mouth technique (inserting MDI mouthpiece between lips and teeth).”

that’s from the asthma guidelines. i don’t really understand why there is a disconnect. it gets the drug more into the lungs, but there’s no clinical benefit. does that mean you don’t need more drug in the lungs? or there is more to asthma than just the lungs? hm. disconnects make you think. but the thoughts usually don’t go anywhere.